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Mental health research and treatment

Mental-health conditions, ADHD, psychiatric treatments, psychedelics, and clinical research.

5,138 stories · 55 in 30 days · Updated Sep 28, 2026

The pace of conversation

Posts per month

2020-01: 76 posts2020-02: 52 posts2020-03: 50 posts2020-04: 34 posts2020-05: 41 posts2020-06: 53 posts2020-07: 56 posts2020-08: 53 posts2020-09: 61 posts2020-10: 52 posts2020-11: 40 posts2020-12: 69 posts2021-01: 64 posts2021-02: 42 posts2021-03: 59 posts2021-04: 69 posts2021-05: 62 posts2021-06: 61 posts2021-07: 55 posts2021-08: 62 posts2021-09: 42 posts2021-10: 69 posts2021-11: 63 posts2021-12: 56 posts2022-01: 56 posts2022-02: 58 posts2022-03: 63 posts2022-04: 72 posts2022-05: 70 posts2022-06: 51 posts2022-07: 64 posts2022-08: 58 posts2022-09: 71 posts2022-10: 62 posts2022-11: 84 posts2022-12: 74 posts2023-01: 82 posts2023-02: 63 posts2023-03: 69 posts2023-04: 53 posts2023-05: 62 posts2023-06: 77 posts2023-07: 66 posts2023-08: 57 posts2023-09: 54 posts2023-10: 75 posts2023-11: 70 posts2023-12: 79 posts2024-01: 72 posts2024-02: 72 posts2024-03: 72 posts2024-04: 88 posts2024-05: 76 posts2024-06: 69 posts2024-07: 65 posts2024-08: 72 posts2024-09: 84 posts2024-10: 68 posts2024-11: 64 posts2024-12: 52 posts2025-01: 67 posts2025-02: 59 posts2025-03: 58 posts2025-04: 74 posts2025-05: 71 posts2025-06: 60 posts2025-07: 59 posts2025-08: 67 posts2025-09: 71 posts2025-10: 63 posts2025-11: 87 posts2025-12: 67 posts2026-01: 71 posts2026-02: 69 posts2026-03: 67 posts2026-04: 59 posts2026-05: 49 posts2026-06: 71 posts2026-07: 44 posts2026-08: 68 posts2026-09: 52 posts
2020-012026-09

Posts per month · first and latest months may be partial.

01 / EXPLORE THROUGH TIME

Timeline

Start with the latest. Scroll back through time, or zoom in for more.

Year by yearUp to 5 stories per year
2026550 stories
I-have-ADHD: A skill to stop coding agents from burying the answer↗ github.com · HN · 371 comments · 542 points · Sep 08, 2026
It's getting harder to focus every day↗ glyphack.com · HN · 420 comments · 794 points · Jul 24, 2026
I was recently diagnosed with anti-NMDA receptor encephalitis↗ burntsushi.net · HN · 249 comments · 753 points · Jun 03, 2026
UCLA discovers first stroke rehabilitation drug to repair brain damage (2025)↗ stemcell.ucla.edu · HN · 102 comments · 448 points · May 11, 2026
AI fatigue is real and nobody talks about it↗ siddhantkhare.com · HN · 320 comments · 471 points · Feb 08, 2026
2025803 stories
Show HN: Autism Simulator↗ autism-simulator.vercel.app · HN · 857 comments · 779 points · Oct 01, 2025
Huntington's disease treated for first time↗ bbc.com · HN · 121 comments · 709 points · Sep 24, 2025
Notes on Managing ADHD↗ borretti.me · HN · 330 comments · 633 points · Aug 31, 2025
Engineered Addictions↗ masonyarbrough.substack.com · HN · 451 comments · 720 points · Jun 28, 2025
My 16-month theanine self-experiment↗ dynomight.net · HN · 435 comments · 817 points · Mar 09, 2025
2024854 stories
Psilocybin bests SSRI for major depression in first long-term comparison↗ medscape.com · HN · 379 comments · 582 points · Oct 12, 2024
Ask HN: Former gifted children with hard lives, how did you turn out?↗ news.ycombinator.com · HN · 327 comments · 375 points · Sep 14, 2024
An FDA approved device offers a new treatment for tinnitus↗ npr.org · HN · 178 comments · 303 points · Apr 15, 2024
AlphaFold Found Possible Psychedelics↗ nature.com · HN · 122 comments · 307 points · Jan 18, 2024
The teen mental illness epidemic is international (2023)↗ afterbabel.com · HN · 875 comments · 498 points · Jan 10, 2024
2023807 stories
Ask HN: Should I medicate my ADHD?↗ news.ycombinator.com · HN · 104 comments · 49 points · Dec 27, 2023
Adolescent boys struggle with disorganization and distraction↗ wsj.com · HN · 14 comments · 36 points · Dec 09, 2023
Antidepressants or Tolkien↗ antidepressantsortolkien.vercel.app · HN · 4 comments · 52 points · Nov 08, 2023
Ask HN: How to navigate the world as a brain-damaged 17 year old?↗ news.ycombinator.com · HN · 29 comments · 73 points · Jun 28, 2023
Ask HN: At 45, I can't seem to read as well anymore↗ news.ycombinator.com · HN · 44 comments · 36 points · Jan 10, 2023
2022783 stories
For some with ADHD, the low rumble of brown noise quiets the brain↗ washingtonpost.com · HN · 309 comments · 392 points · Nov 20, 2022
My ADHD founder toolbox↗ hypatia.ca · HN · 398 comments · 455 points · Nov 17, 2022
NightWare helps disrupt nightmares for those with PTSD↗ apple.com · HN · 262 comments · 377 points · Nov 08, 2022
I'm an addict↗ tarunreddy.bearblog.dev · HN · 583 comments · 611 points · May 18, 2022
Loving Someone with Depression↗ mentalhealth.org.uk · HN · 282 comments · 502 points · Jan 02, 2022
2021704 stories
Experimental depression treatment is nearly 80% effective in controlled study↗ med.stanford.edu · HN · 321 comments · 611 points · Dec 30, 2021
ADHD Accommodations Guide↗ adhdatwork.add.org · HN · 349 comments · 440 points · Dec 24, 2021
First federal grant for psychedelic treatment research in 50 years↗ hopkinsmedicine.org · HN · 116 comments · 512 points · Oct 18, 2021
Idempotence now prevents pain later↗ ericlathrop.com · HN · 127 comments · 427 points · Apr 07, 2021
Addiction to Outrage (2020)↗ medium.com · HN · 240 comments · 465 points · Mar 28, 2021
2020637 stories
How to deal with extreme physical pain↗ hanselman.com · HN · 335 comments · 568 points · Oct 30, 2020
MS treatment a step closer after drug shown to repair nerve coating↗ theguardian.com · HN · 137 comments · 491 points · Sep 25, 2020
Let’s avoid talk of ‘chemical imbalance’: it’s people in distress↗ psyche.co · HN · 384 comments · 511 points · Jul 16, 2020
A new form of brain stimulation relieved severe depression in a small study↗ med.stanford.edu · HN · 253 comments · 430 points · Apr 07, 2020
ADHD, a Lifelong Struggle (2018)↗ gekk.info · HN · 441 comments · 458 points · Jan 23, 2020
Scroll through time ↕

02 / CATCH UP

The conversation now

Popular stories, with attention fading over roughly two weeks.

I-have-ADHD: A skill to stop coding agents from burying the answer↗ github.com · HN · 371 comments · 542 points · Sep 08, 2026
Reverse engineering my ADHD test↗ nullpt.rs · HN · 238 comments · 318 points · Aug 27, 2026
Doctors are finally learning to manage antidepressant withdrawal↗ newscientist.com · HN · 369 comments · 302 points · Aug 27, 2026
MentalHealthBench↗ openai.com · HN · 15 comments · 36 points · Sep 24, 2026
African elephants putatively self-medicate with medicinal plants↗ nature.com · HN · 0 comments · 16 points · Sep 24, 2026

03 / GO DEEPER

Follow your curiosity

Find a particular story, revisit a year, or see what resonated.

Highest rated · the last 30 days

I-have-ADHD: A skill to stop coding agents from burying the answer↗ github.com · HN · 371 comments · 542 points · Sep 08, 2026
Ask HN: How do you survive a job you hate which is slowly making you sick?↗ news.ycombinator.com · HN · 70 comments · 53 points · Sep 02, 2026
Dextroproporphan: An Analogue for a Better Dextromethorphan?↗ monfak.top · HN · 16 comments · 39 points · Sep 02, 2026
MentalHealthBench↗ openai.com · HN · 15 comments · 36 points · Sep 24, 2026
African elephants putatively self-medicate with medicinal plants↗ nature.com · HN · 0 comments · 16 points · Sep 24, 2026
Alzheimer's trial to test drug on people without symptoms to test prevention↗ theguardian.com · HN · 5 comments · 13 points · Sep 06, 2026
Magic-mushroom compound blocks a side effect of chemotherapy in mice↗ nature.com · HN · 0 comments · 11 points · Sep 08, 2026
Everyone has ADHD because we made it up↗ neubroscience.substack.com · HN · 9 comments · 10 points · Sep 28, 2026
ADHD as a circadian rhythm disorder: evidence and implications for chronotherapy↗ frontiersin.org · HN · 0 comments · 10 points · Sep 23, 2026
Scientists Find a Subtle Clue to ADHD Hidden in the Eyes↗ sciencealert.com · HN · 1 comments · 8 points · Sep 14, 2026

10 stories shown.

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